Another study has been published that supports a relationship between physical fitness and brain volume. This study explored the rate of brain shrinkage or cell loss in persons with mild Alzheimer’s disease. Subjects had their peak oxygen demand measured while running on a treadmill and this was related to their brain shrinkage as estimated by MRI scan.

Results indicate that those persons suffering AD who were more physically fit had less brain shrinkage than less-fit participants. Curiously, these same persons did not do significantly better on tests for mental performance. The authors suggested that there were not enough participants to see the difference in cognitive performance and that the study used only one measurement point which prohibited demonstration of a conclusion.

However, this study together with other research further underscores an important relationship between blood flow, cardiac health, and brain health (e.g. brain fitness).

Get your tennis shoes on and get moving!

Try the Fit Brains brain games.

The summer months bring warm weather, blue sky, and plenty of sunshine. For some, if not most, we may notice our mood becomes a bit happier. Is there a relationship between the sunshine and our mood? Probably, but why?

Some studies have reported a relationship between Vitamin D that is derived from sunshine and different physiological measures in the human body. Sunlight has also been related to mood with a disorder known as “Seasonal Affective Disorder” in which those not exposed to enough sunlight can become depressed. Indeed, special lights have been prescribed for those with seasonal affective disorder to help their brains gain more ultraviolet exposure to lift their mood.

Sunshine also tends to come with blue sky, relates to an increased ability to get outside and move about in nature, and to recreate more. Each of these factors is important and is related indirectly to mood enhancement.

It is important to pay attention to your own mood and determine what environmental factors may help you feel happier. If sunshine and blue sky lift your spirits try to prescribe yourself increased time outside. You may feel more energy, higher sense of self and increased productivity.

Take the suntan lotion with you!

Try the Fit Brains brain games.

Recent data indicates Americans are living longer than ever before as life expectancy hit 78.1 years in 2006. Rates for 14 of the top 15 causes of death fell in 2006 according the US Centers for Disease Control and Prevention. The most significant decline in cause of death was attributed to influenza and pneumonia that fell nearly 13% from the previous year.

Life expectancy of 78.1 is up from 77.8 years in 2005 representing a continued rise over the past decades. Women have a life expectancy of 80.7 years while men remain somewhat behind at 75.4 years. Racial disparities also exist with white women’s life expectancy at 81 years compared to 76.9 for black women. White men’s life expectancy was 76 years and black men at 70.

The top two causes of death include heart disease and cancer followed by stroke, chronic lower respiratory diseases such as emphysema and then accidents. Alzheimer’s disease, the most common form of dementia, is now the sixth leading cause of death in the U.S.

Gains made in life expectancy represent an opportunity for continued years of quality of life. Getting started earlier in life with a proactive lifestyle (physical activity, brain fitness, brain games etc.) including that designed for the heart and brain can help to maximize the quality with the increased quantity of life.

Try the Fit Brains brain games.

I was very proud of myself recently when I generated enough determination to quit my perceived addiction to caffeine in the form of coffee. While it is true that I only consumed one cup of coffee in the morning to get my jump on the day, it is also true that my brain demanded that one cup. I know this because when I stopped or missed my cup of coffee I felt a bit sluggish and then the headaches set in if I did not get the fix for several days. We refer to this as an addiction, though some do not like to hear that word to describe their (my) behavior.

After nearly one month of not consuming any coffee and getting through the withdrawal symptoms, I pick up a new research discovery in the Journal of Neuroinflammation (volume 6, 2008) that reports caffeine blocks disruption of blood brain barrier in a rabbit model of Alzheimer’s disease. It seems caffeine consumed in the equivalent of one cup of coffee daily protects against high cholesterol diet induced increases in disruptions of the blood brain barrier, and caffeine might be useful in the treatment of Alzheimer’s.
If high levels of serum cholesterol and disruption of the blood brain barrier are indeed underlying mechanisms in the pathogenesis of Alzheimer’s it suggests I need to reconsider starting my habit again!

The important message in the story is that we continue to monitor the new findings of lifestyle and brain health and change our behavior accordingly. This should not occur in an impulsive way. Rather, the negative effects need to be weighed against the positive effects of particular behaviors. For me, I think I will restart my consumption of coffee, but keep it to ½ cup a day. Moderation is typically a great idea. In the meantime, I will keep an eye out for replication of this finding on the relationship between caffeine and protection against Alzheimer’s.

What a great time to be alive if you are interested in your own brain and how to promote its health! With the daily reports of a new finding on how to promote brain health, the development of new companies with products for brain fitness (e.g. brain games), and with the boomers generating a booming interest in this part of their being, we really are in the “golden era of brain health.”

I am so very fortunate to have been involved with brain health more than a decade ago and to witness what I described then as the emerging “Brain Wave” that was coming. It is here and we will all be better for the fact that the human brain has found its way onto the radar screen of health.

A national and world wide discussion of the human brain with a focus on proactive lifestyle towards promotion of brain health is a great and needed thing. Dementia is a real problem and a growing concern. We have the ability to be proactive and to focus on an optimistic and positive path forward as we try to implement research-based behaviors to brain reserve. By building our own brain reserve across our lifespan we probably increase our chances of delaying the onset of neurodegenerative diseases such as Alzheimer’s.

The next step to this growing brain wave is for the governmental bodies to pass legislation that incorporates national emphasis on the brain similar to what we have done for the heart; for health care payers to include incentives for leading a brain health lifestyle that might recognize lifelong learning, brain fitness, use of pedometers, diet, and meditation as critical ingredients to brain health, and for continued innovation in the business world to apply research to the market.

What a great day to be interested in promoting your own brain health!

A study published in online Neurology 3-27-08 indicates belly fat is linked to increased risk of dementia. Rachel Whitmer, a researcher at Kaiser Permanente Division of Research noted that belly fat increases the risk of diabetes, heart disease, and stroke. However, her research on 6,583 men and women ages 40-45 living in northern

California found that belly fat was also related to increased risk of dementia.

Indeed those who were obese (30 pounds or more over a healthy weight) and had collected belly fat in their 40s were 3.6 times more likely to develop dementia during the 30 to 40 year study. Even those who were not obese, yet had extra weight around the waist or belly, were 1.8 times more likely to develop dementia compared to those who were lean all over.Whitmer stated that “it is not simply about weight, but where you carry your weight.” She noted that people who are predisposed to carry their fat in their belly region may be at risk. Fat cells in the stomach secrete hormones that may play a role in diseases such as diabetes, heart disease, and now perhaps dementia.

The good news is that anyone with belly fat in their 40s can adopt a lifestyle of diet and exercise that can reduce such fat and reduce the risk of disease related to the fat. Time to get moving and eating healthier!

We have no cure or perfect prevention against progressive dementia such as Alzheimer’s disease (AD). However, research over the past decade or more has established consistent links between lifestyle and the ability to delay the onset of such dementias. I have proposed a “Brain Health Lifestyle” to include five major factors: (1) physical activity, (2) mental stimulation, (3) socialization, (4) nutrition, (5) and spirituality.

A recent interview on ABC News suggested that physical exercise may be the best means of preventing AD today, better than medications, intellectual activity, and supplements. Studies on mice bred to develop plaques in their brains consistent with AD were exposed to an exercise regimen or not. Those mice that exercised had 50 to 80 percent less plaque than the brains of mice that were passive. Other studies have demonstrated generation of new brain cells in animals that exercise and a relationship in humans between physical exercise and increased cognitive performance.

One important point is that our body does not operate in a fragmented manner. I describe the brain and body as a miraculous symphony. One system directly impacts another and both health and disease effects can be experienced as a result throughout the body. Exercise is one example of a behavior that has positive impact on multiple systems of the body including the brain. The same can be said for the other four brain health lifestyle behaviors noted above.

While I am not yet sure that any one behavior such as exercise is better than another in promoting brain health, I do champion regular exercise as a very important behavior with positive brain health effects. My view is to approach brain health from an integrated manner using the five part brain health lifestyle. This approach fits with the complex integrated reality of our bodies and brains.

Everyone experiences moments when we feel sluggish or perhaps hyperactive. Sometimes our brains feel like they are stuck in mud while other times we can solve almost any problem we confront. Interestingly, these cycles of mental energy or arousal may occur within a 24 hour time period, our circadian rhythm.

Some of us have our creative time or the time we perform best mentally in the morning hours. Others have their greatness expressed in the evening hours. There is no right versus wrong, simply different. Some people who work after midnight or in a mine shaft that has no natural light can experience a different circadian rhythm than those who work during the day and have exposure to natural sunlight. Sleep disorders, depression, and cognitive problems can result from altered sleep wake cycles.

There is no clear explanation for when arousal is highest in some and lowest for others. Some factors that can enhance or reduce mental energy or arousal include the following:

• Amount of daily exercise
• Amount of sleep in 24 hours
• Types of foods consumed
• Water intake and hydration
• Exposure to sunlight
• Prescribed Medication and substance abuse
• Mental challenge during the day

One of the best methods to increase mental energy is to increase blood flow to the brain through movement. This can include a brisk walk, aerobics, brain games, swimming, and even a dance. Fresh air can also rejuvenate a sluggish brain and increase water intake to remain hydrated during the day. Sugar can put the brain to sleep in some cases or make it feel like a good nap is needed. Caffeine can provide a quick boost, but may result in a type of mental crash later in the day.

It is a good idea to first identify what periods of the day your brain is alert and productive and when it is sluggish. Try to identify what factors might be causing the onset of sluggishness and consider the brain tips suggested above.

A mentally alert brain is critical to health and to productivity.

The market has witnessed a surge in the brain fitness software industry. More companies are purporting to be the best at training your brain and helping to sharpen cognitive or thinking skills.

One primary concern for this industry is to create software that is both fun and personally relevant. In fact, a primary focus of FitBrains is to be the leader of fun and personal relevance within the industry of brain fitness software. I believe that brain games can be both fun and have real life and personal value to a consumer.

We are all confronted with life’s daily challenges, each of which places demands on our brain for solutions or action. It is within this arena that FitBrains has captured the personal value: creating brain games that actually tap into real world challenges for the consumer. How many times have you lost a pair of socks in the laundry, forgotten the name of someone you met, misplaced your car keys or perhaps the car itself in the parking garage? Life provides us with real world games and the opportunity for real world mental exercise.

FitBrains takes this reality and champions brain fitness for the fun and personally relevant. We believe your arousal level will increase and you will be more deeply engaged in our brain games. Why? The task is more valuable or meaningful to you as a person. Companies that simply develop memory games or language games without the value of personal relevance are simply tasks to be completed. Personalization sparks long term commitment by the consumer for a healthy brain.

Your brain operates electrically and chemically. Neurochemicals form the dynamic foundation for our thoughts and emotions. Many neurochemicals have been identified while many more have not. Neurochemicals important to mood include Serotonin, Neuropinephrine, Neuroadrenaline, and Dopamine. These neurochemicals remain in healthy balance for most of us, but for some there is imbalance and a mood disorder can result.

Effects of a mood disorder such as depression or mania include functional decline, interpersonal difficulty, and cognitive impairment. Depression is far more common than realized and represents a major chronic illness similar to high blood pressure. Depression not only affects the specific person, but it can also affect negatively those close to the patient and to potential colleagues. Depression and mania impairs thinking by reducing focus, attention, memory, and ability to execute plans. A depressed brain cannot process as deeply as necessary and this can result in rather significant cognitive impairment at times. Uncontrolled mania results in high distractibility, poor attention, and generally impaired cognitive functions across the board.

Treatments for mood disorder are effective and include use of antidepressants, mood stabilizers for mania, psychotherapy, and following a brain health lifestyle as espoused by Dr. Nussbaum (www.paulnussbaum.com). Use of software similar to that of FitBrains that helps to stimulate mental activity can also be of some use for a brain that may be sluggish. The most important thing is to first identify depression when it arises, take it seriously, and get some help.